| 2023-12 |
A bivalent form of a RBD-specific synthetic antibody effectively neutralizes SARS-CoV-2 variants |
Antiviral Research
|
| 2023-09 |
A natural variation in the RNA polymerase of severe fever with thrombocytopenia syndrome virus enhances viral replication and in vivo virulence |
Journal of Medical Virology
|
| 2023-09 |
Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser |
Experimental and Molecular Medicine
|
| 2023-04 |
Oligomeric states of ASC specks regulate inflammatory responses by inflammasome in the extracellular space |
Cell Death Discovery
|
| 2023-04 |
Novel bispecific human antibody platform specifically targeting a fully open spike conformation potently neutralizes multiple SARS-CoV-2 variants |
Antiviral Research
|
| 2022-12 |
Computational design of a neutralizing antibody with picomolar binding affinity for all concerning SARS-CoV-2 variants |
MABS
|
| 2022-12 |
Unraveling the Pathobiological Role of the Fungal KEOPS Complex in Cryptococcus neoformans |
mBio
|
| 2022-11 |
Catalytic DxD motif caged in Asx-turn and Met-aromatic interaction attenuates the pathogenic glycosylation of SseK2/NleB2 effectors |
SCIENTIFIC REPORTS
|
| 2022-09 |
Cyclin-dependent kinase 1 depolymerizes nuclear lamin filaments by disrupting the head-to-tail interaction of the lamin central rod domain |
Journal of Biological Chemistry
|
| 2021-09 |
Crosstalk between WNT and STAT3 is mediated by galectin-3 in tumor progression |
GASTRIC CANCER
|
| 2021-08 |
Structural and Functional Characterizations of Cancer Targeting Nanoparticles Based on Hepatitis B Virus Capsid |
International Journal of Molecular Sciences
|
| 2021-06 |
A Novel Therapeutic Anti-ErbB3, ISU104 Exhibits Potent Antitumorigenic Activity by Inhibiting Ligand Binding and ErbB3 Heterodimerization |
MOLECULAR CANCER THERAPEUTICS
|
| 2021-06 |
Role of AmpG in the resistance to β‑lactam agents, including cephalosporins and carbapenems: candidate for a novel antimicrobial target |
ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS
|
| 2021-06 |
NleB/SseKs ortholog effectors as a general bacterial monoglycosyltransferase for eukaryotic proteins |
CURRENT OPINION IN STRUCTURAL BIOLOGY
|
| 2021-04 |
CHIP-mediated hyperubiquitylation of tau promotes its self-assembly into the insoluble tau filaments |
CHEMICAL SCIENCE
|
| 2021-01 |
Computationally-guided design and affinity improvement of a protein binder targeting a specific site on HER2 |
Computational and Structural Biotechnology Journal
|
| 2020-12 |
Direct binding of TFEα opens DNA binding cleft of RNA polymerase |
NATURE COMMUNICATIONS
|
| 2020-08 |
Viscous-medium-based crystal support in a sample holder for fixed-target serial femtosecond crystallography |
JOURNAL OF APPLIED CRYSTALLOGRAPHY
|
| 2020-05 |
The in vivo functions of ARPF2 and ARRS1 in ribosomal RNA processing and ribosome biogenesis in Arabidopsis |
JOURNAL OF EXPERIMENTAL BOTANY
|
| 2020-04 |
Colorectal adenocarcinoma-derived EGFR mutants are oncogenic and sensitive to EGFR-targeted monoclonal antibodies, cetuximab and panitumumab |
INTERNATIONAL JOURNAL OF CANCER
|
| 2019-10 |
Structural analysis of fungal pathogenicity-related casein kinase alpha subunit, Cka1, in the human fungal pathogen Cryptococcus neoformans |
SCIENTIFIC REPORTS
|
| 2019-09 |
Protein kinase A-induced phosphorylation at the Thr154 affects stability of DJ-1 |
PARKINSONISM & RELATED DISORDERS
|
| 2019-08 |
Structural Study of Monomethyl Fumarate-Bound Human GAPDH |
MOLECULES AND CELLS
|
| 2019-02 |
RSL Class II Transcription Factors Guide the Nuclear Localization of RHL1 to Regulate Root Hair Development |
PLANT PHYSIOLOGY
|
| 2019-01 |
Non-cryogenic structure of a chloride pump provides crucial clues to temperature-dependent channel transport efficiency |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2018-12 |
Structural insights showing how arginine is able to be glycosylated by pathogenic effector proteins |
BMB REPORTS
|
| 2018-10 |
Structural basis for arginine glycosylation of host substrates by bacterial effector proteins |
NATURE COMMUNICATIONS
|
| 2018-10 |
Crystal structure of GSK3β in complex with the flavonoid, morin |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2018-06 |
A missense allele of KARRIKIN-INSENSITIVE2 impairs ligand-binding and downstream signaling in Arabidopsis thaliana |
JOURNAL OF EXPERIMENTAL BOTANY
|
| 2018-05 |
Crystal structure of human dual-specificity tyrosine-regulated kinase 3 reveals new structural features and insights into its autophosphorylation |
JOURNAL OF MOLECULAR BIOLOGY
|
| 2017-09 |
Purification, crystallization and X-ray diffraction of heparan sulfate bounded human RAGE |
BIO DESIGN
|
| 2017-06 |
Active Site Engineering of ω?Transaminase Guided by Docking Orientation Analysis and Virtual Activity Screening |
ACS CATALYSIS
|
| 2017-05 |
Niclosamide is a potential therapeutics for familial adenomatosis polyposis by disrupting Axin-GSK3 interaction |
ONCOTARGET
|
| 2017-01 |
Constitutive activation of T cells by γ2-herpesviral GPCR through the interaction with cellular CXCR4 |
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
|
| 2016-11 |
New structural insight of C-terminal region of Syntenin-1, enhancing the molecular dimerization and inhibitory function related on Syndecan-4 signaling. |
SCIENTIFIC REPORTS
|
| 2016-08 |
Crystal structure and functional characterization of a light-driven chloride pump having an NTQ motif |
NATURE COMMUNICATIONS
|
| 2016-07 |
Monomerization and ER Relocalization of GRASP Is a Requisite for Unconventional Secretion of CFTR |
TRAFFIC
|
| 2016-06 |
Endosomal acidic pH-induced conformational changes of a cytosol-penetrating antibody mediate endosomal escape. |
JOURNAL OF CONTROLLED RELEASE
|
| 2016-03 |
Spread of Mutant Middle East Respiratory Syndrome Coronavirus with Reduced Affinity to Human CD26 during the South Korean Outbreak. |
mBio
|
| 2016-02 |
GC1118, an Anti-EGFR Antibody with a Distinct Binding Epitope and Superior Inhibitory Activity against High-Affinity EGFR Ligands. |
MOLECULAR CANCER THERAPEUTICS
|
| 2016-01 |
N-linked glycosylation plays a crucial role in the secretion of HMGB1 |
JOURNAL OF CELL SCIENCE
|
| 2015-12 |
In Vitro and In Vivo Investigation of the Inhibition of Trypanosoma brucei Cell Growth by Lipophilic Bisphosphonates |
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
|
| 2015-10 |
Enzymatic Prenylation and Oxime Ligation for the Synthesis of Stable and Homogeneous Protein-Drug Conjugates for Targeted Therapy |
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
|
| 2015-07 |
Crystal structure of syndesmos and its interaction with Syndecan-4 proteoglycan |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2015-06 |
Solution structure of the transmembrane 2 domain of the human melanocortin-4 receptor in sodium dodecyl sulfate (SDS) micelles and the functional implication of the D90N mutant |
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
|
| 2015-06 |
Akt-mediated phosphorylation increases the binding affinity of hTERT for importin α to promote nuclear translocation. |
JOURNAL OF CELL SCIENCE
|
| 2015-03 |
Structural analysis of mouse GSK3β fused with the LRP6 peptide |
BIO DESIGN
|
| 2015-01 |
Co-expression of human agouti-related protein enhances expression and stability of human melanocortin-4 receptor |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2014-12 |
Lattice Corneal Dystrophy Type IIIA With Hyaline Component From a Novel A620P Mutation and Distinct Surgical Treatments |
CORNEA
|
| 2014-04 |
Computational Design of Bingding Proteins to EGFR Domain II |
PLOS ONE
|
| 2014-04 |
The crystal structure of MPK38 in complex with OTSSP167, an orally administrative MELK selective inhibitor |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2014-03 |
Current advances in the development of G-protein-coupled receptor structure and their future application in drug design |
BIO DESIGN
|
| 2014-02 |
The structures of the kinase domain and UBA domain of MPK38 suggest the activation mechanism for kinase activity |
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
|
| 2013-12 |
Structural Basis for the Inhibition of Human Lysozyme by PliC from Brucella abortus |
BIOCHEMISTRY
|
| 2013-10 |
Functional interplay between Aurora B kinase and Ssu72 phosphatase regulates sister chromatid cohesion |
NATURE COMMUNICATIONS
|
| 2013-10 |
Structure of the periplasmic copper-binding protein CueP from Salmonella enterica serovar Typhimurium |
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
|
| 2013-02 |
Backbone Dynamics of an Atypical Orphan Response Regulator Protein, Helicobacter pylori 1043 |
Molecules and Cells
|
| 2012-10 |
Hsp90 rescues PTK6 from proteasomal degradation in breast cancer cells |
BIOCHEMICAL JOURNAL
|
| 2011-09 |
Crystal Structure of Fushi Tarazu Factor 1 Ligand Binding Domain/Fushi Tarazu Peptide Complex Identifies New Class of Nuclear Receptors |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2011-09 |
Identification of lipopolysaccharide-binding peptide regions within HMGB1 and their effects on subclinical endotoxemia in a mouse model |
EUROPEAN JOURNAL OF IMMUNOLOGY
|
| 2011-07 |
Analysis of deposit depth and morphology in granular corneal dystrophy type 2 using fourier domain optical coherence tomography |
CORNEA
|
| 2011-04 |
Functional Implications of an Intermeshing Cogwheel-like Interaction between TolC and MacA in the Action of Macrolide-specific Efflux Pump MacAB-TolC |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2010-12 |
Periplasmic Domain of CusA in an Escherichia coli Cu+/Ag+ Transporter Has Metal Binding Sites |
Journal Of Microbiology
|
| 2010-09 |
Parkin Directly Modulates 26S Proteasome Activity |
JOURNAL OF NEUROSCIENCE
|
| 2010-06 |
Prevalence of granular corneal dystrophy type 2 (avellino corneal dystrophy) in the korean population |
Ophthalmic Epidemiology
|
| 2010-05 |
Mitomycin C does not inhibit exacerbation of granular corneal dystrophy type II induced by refractive surface ablation |
Cornea
|
| 2010-04 |
Crystal structure and functional insight of HP0420-homolog from Helicobacter felis |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2010-04 |
Involvement of TGF-beta Receptor- and Integrin-Mediated Signaling Pathways in the Pathogenesis of Granular Corneal Dystrophy II |
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
|
| 2010-03 |
The structure of the trimer of human 4-1BB ligand is unique among members of the tumor necrosis factor superfamily |
The Journal of biological chemistry
|
| 2010-02 |
Identification of potential and selective collagenase, gelatinase inhibitors from Crataegus pinnatifida |
Bioorganic & Medicinal Chemistry Letters
|
| 2010-01 |
Molecular mechanism for the regulation of human ACC2 through phosphorylation by AMPK |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2009-12 |
Characterization of a New Metallo-beta-Lactamase Gene, bla(NDM-1), and a Novel Erythromycin Esterase Gene Carried on a Unique Genetic Structure in Klebsiella pneumoniae Sequence Type 14 from India |
Antimicrobial Agents And Chemotherapy
|
| 2009-07 |
Decreased Catalase Expression and Increased Susceptibility to Oxidative Stress in Primary Cultured Corneal Fibroblasts from Patients with Granular Corneal Dystrophy Type II |
AMERICAN JOURNAL OF PATHOLOGY
|
| 2009-06 |
Corneal Dystrophy-associated R124H Mutation Disrupts TGFBI Interaction with Periostin and Causes Mislocalization to the Lysosome |
Journal of Biological Chemistry
|
| 2009-03 |
A novel in-frame deletion in the factor V C1 domain associated with severe coagulation factor V deficiency in a Korean family |
Blood Coagulation & Fibrinolysis
|
| 2009-02 |
Solution Structure of the DNA Binding Domain of Rice Telomere Binding Protein RTBP1 |
Biochemistry
|
| 2008-08 |
Sensing domain and extension rate of a family B-type DNA polymerase determine the stalling at a deaminated base |
Journal Of Microbiology And Biotechnology
|
| 2008-04 |
Structure of the DNA-binding domain of NgTRF1 reveals unique features of plant telomere-binding proteins |
Nucleic Acids Research
|
| 2008-03 |
Crystal structure of Pfu, the high fidelity DNA polymerase from Pyrococcus furiosus |
International Journal Of Biological Macromolecules
|
| 2008-01 |
Structural analysis of sialyltransferase PM0188 from Pasteurella multocida complexed with donor analogue and acceptor sugar |
BMB REPORTS
|
| 2007-11 |
Structure of an atypical orphan response regulator protein supports a new phosphorylation-independent regulatory mechanism |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2007-09 |
Crystallization and preliminary crystallographic analysis of the fourth FAS1 domain of human BigH3 |
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS
|
| 2007-07 |
Crystal structure of hyperthermophilic esterase EstE1 and the relationship between its dimerization and thermostability properties |
BMC STRUCTURAL BIOLOGY
|
| 2007-01 |
곤충세포에서 새로운 퓨전 단백질인 초파리 유래 PGRP-LB를 이용한 인간 PTK6의 과발현 및 생산 |
생명과학회지
|
| 2006-09 |
Purification and characterization of the functional catalytic domain of PKR-like endoplasmic reticulum kinase expressed in Escherichia coli |
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
|
| 2006-05 |
Crystallization and preliminary X-ray crystallographic study of HP1043, a Helicobacter pylori orphan response regulator |
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
|
| 2006-04 |
Analysis of the thermostability determinants of hyperthermophilic esterase EstE1 based on its predicted three-dimensional structure |
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
|
| 2006-02 |
Crystallization and preliminary X-ray crystallographic analysis of EstE1, a new and thermostable esterase cloned from a metagenomic library |
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS
|
| 2006-02 |
Mean curvature as a major determinant of β-sheet propensity |
BIOINFORMATICS
|
| 2006-01 |
Crystallization and preliminary X-ray crystallographic study of the extracellular domain of the 4-1BB ligand, a member of the TNF family |
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS
|
| 2006-01 |
Crystallization and preliminary X-ray crystallographic analysis of the α-2,6-sialyltransferase PM0188 from Pasteurella multosida |
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS
|
| 2003-09 |
An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors |
MOLECULAR CELL
|
| 2003-02 |
Structure of the Extracellular Region of HER2 Alone and Complexed with the Herceptin Fab |
NATURE
|
| 2003-01 |
EGF Activates Its Receptor by Removing Interactions that Autoinhibit Ectodomain Dimerization |
MOLECULAR CELL
|
| 2002-08 |
Structure of the Extracellular Region of HER3 Reveals an Interdomain Tether |
SCIENCE
|
| 2002-01 |
Cyclomaltodextrinase, neopullulanase, and maltogenic amylase are nearly indistinguishable from each other |
J KMS
|
| 2000-11 |
Role of Catalytic Residues in Enzymatic Mechanisms of Homologous Ketosteroid Isomerases |
JOURNAL OF BIOCHEMISTRY
|