| 2024-04 |
Dual-specificity kinase DYRK3 phosphorylates p62 at the Thr-269 residue and promotes melanoma progression |
Journal of Biological Chemistry
|
| 2024-04 |
The SCF-FBW7β E3 ligase mediates ubiquitination and degradation of the serine/threonine protein kinase PINK1 |
Journal of Biological Chemistry
|
| 2023-10 |
USP7 attenuates endoplasmic reticulum stress-induced apoptotic cell death through deubiquitination and stabilization of FBXO7 |
PLoS ONE
|
| 2023-03 |
E3 ligase adaptor FBXO7 contributes to ubiquitination and proteasomal degradation of SIRT7 and promotes cell death in response to hydrogen peroxide |
Journal of Biological Chemistry
|
| 2022-12 |
DYRK3 phosphorylates SNAPIN to regulate axonal retrograde transport and neurotransmitter release |
Cell Death Discovery
|
| 2022-11 |
The ubiquitin–proteasome system and autophagy mutually interact in neurotoxin-induced dopaminergic cell death models of Parkinson's disease |
FEBS Letters
|
| 2022-10 |
Tollip negatively regulates mitophagy by promoting the mitochondrial processing and cytoplasmic release of PINK1 |
BMB Reports
|
| 2022-10 |
Covalent conjugation of ubiquitin-like ISG15 to apoptosis inducing factor exacerbates toxic stimuli-induced apoptotic cell death |
Journal of Biological Chemistry
|
| 2021-12 |
Precise control of mitophagy through ubiquitin proteasome system and deubiquitin proteases and their dysfunction in Parkinson’s disease |
BMB reports
|
| 2021-12 |
FBXO7 triggers caspase 8-mediated proteolysis of the transcription factor FOXO4 and exacerbates neuronal cytotoxicity |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2021-01 |
Protein phosphatase PPM1B inhibits DYRK1A kinase through dephosphorylation of pS258 and reduces toxic tau aggregation |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2020-06 |
Death-associated protein kinase 1 phosphorylates α-synuclein at Ser129 and exacerbates rotenone-induced toxic aggregation of α-synuclein in dopaminergic SH-SY5Y cells |
Experimental Neurobiology
|
| 2020-06 |
Human telomerase reverse transcriptase positively regulates mitophagy by inhibiting the processing and cytoplasmic release of mitochondrial PINK1 |
CELL DEATH & DISEASE
|
| 2020-01 |
The central regulator p62 between ubiquitin proteasome system and autophagy and its role in the mitophagy and Parkinson’s disease |
BMB REPORTS
|
| 2020-01 |
Mitochondria and Neurodegenerative Diseases: Special Issue of BMB Reports in 2020 |
BMB REPORTS
|
| 2019-01 |
Gintonin Mitigates MPTP-Induced Loss of Nigrostriatal Dopaminergic Neurons and Accumulation of -Synuclein via the Nrf2/HO-1 Pathway |
MOLECULAR NEUROBIOLOGY
|
| 2018-01 |
New insight into transglutaminase 2 and link to neurodegenerative diseases |
BMB REPORTS
|
| 2018-01 |
The ubiquitin E3 ligase CHIP promotes proteasomal degradation of the serine/threonine protein kinase PINK1 during staurosporine-induced cell death |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2018-01 |
Covalent ISG15 conjugation to CHIP promotes its ubiquitin E3 ligase activity and inhibits lung cancer cell growth in response to type I interferon |
CELL DEATH & DISEASE
|
| 2017-12 |
Deubiquitinating enzyme USP22 positively regulates c-Myc stability and tumorigenic activity in mammalian and breast cancer cells |
JOURNAL OF CELLULAR PHYSIOLOGY
|
| 2017-08 |
Human telomerase reverse transcriptase (hTERT) positively regulates 26S proteasome activity |
JOURNAL OF CELLULAR PHYSIOLOGY
|
| 2017-05 |
Leucine-rich repeat kinase 2 (LRRK2) stimulates IL-1β-mediated inflammatory signaling through phosphorylation of RCAN1 |
FRONTIERS IN CELLULAR NEUROSCIENCE
|
| 2017-01 |
Leucine-rich repeat kinase 2 exacerbates neuronal cytotoxicity through phosphorylation of histone deacetylase 3 and histone deacetylation |
HUMAN MOLECULAR GENETICS
|
| 2016-12 |
Estradiol synthesis in gut-associated lymphoid tissue: Leukocyte regulation by a sexually monomorphic system |
ENDOCRINOLOGY
|
| 2016-09 |
Precise assembly and regulation of 26S proteasome and correlation between proteasome dysfunction and neurodegenerative diseases |
BMB REPORTS
|
| 2016-08 |
Covalent ISG15 conjugation positively regulates the ubiquitin E3 ligase activity of parkin |
OPEN BIOLOGY
|
| 2016-07 |
CHIP-mediated degradation of transglutaminase 2 negatively regulates tumor growth and angiogenesis in renal cancer |
ONCOGENE
|
| 2016-06 |
Proteolytic degradation and potential role of onconeural protein cdr2 in neurodegeneration |
CELL DEATH & DISEASE
|
| 2015-09 |
Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression |
MOLECULAR BRAIN
|
| 2015-08 |
Dyrk1A phosphorylates parkin at Ser-131 and negatively regulates its ubiquitin E3 ligase activity |
JOURNAL OF NEUROCHEMISTRY
|
| 2015-07 |
Ubiquitin-specific Protease 22 (USP22) Positively Regulates RCAN1 Protein Levels through RCAN1 De-ubiquitination |
JOURNAL OF CELLULAR PHYSIOLOGY
|
| 2015-05 |
PINK1 phosphorylates transglutaminase 2 and blocks its proteasomal degradation |
JOURNAL OF NEUROSCIENCE RESEARCH
|
| 2015-01 |
The F-box protein FBXO7 positively regulates bone morphogenetic protein-mediated signaling through Lys-63-specific ubiquitination of neurotrophin receptor-interacting MAGE (NRAGE) |
CELLULAR AND MOLECULAR LIFE SCIENCES
|
| 2014-10 |
Reactive oxygen species mediate IL-8 expression in Down syndrome candidate region-1-overexpressed cells |
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
|
| 2014-08 |
Histone Deacetylase 3 Promotes RCAN1 Stability and Nuclear Translocation |
PLOS ONE
|
| 2014-03 |
Direct Interaction and Functional Coupling between Human 5-HT6 Receptor and the Light Chain 1 Subunit of the Microtubule-Associated Protein 1B (MAP1B-LC1) |
PLOS ONE
|
| 2013-12 |
New Perspectives of Dyrk1A Role in Neurogenesis and Neuropathologic Features of Down Syndrome |
Experimental Neurobiology
|
| 2013-10 |
Age-dependent increases in tau phosphorylation in the brains of type 2 diabetic rats correlate with a reduced expression of p62 |
EXPERIMENTAL NEUROLOGY
|
| 2013-03 |
UHRF2, a Ubiquitin E3 Ligase, Acts as a Small Ubiquitin-like Modifier E3 Ligase for Zinc Finger Protein 131 |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2013-01 |
Zinc finger protein 131 inhibits estrogen signaling by suppressing estrogen receptor alpha homo-dimerization |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2012-12 |
PINK1 positively regulates IL-1β-mediated signaling through Tollip and IRAK1 modulation |
JOURNAL OF NEUROINFLAMMATION
|
| 2012-10 |
Covalent NEDD8 Conjugation Increases RCAN1 Protein Stability and Potentiates Its Inhibitory Action on Calcineurin |
PLOS ONE
|
| 2012-10 |
PINK1 stimulates interleukin-1 beta-mediated inflammatory signaling via the positive regulation of TRAF6 and TAK1 |
Cellular and Molecular Life Sciences
|
| 2012-05 |
Small Ubiquitin-like Modifier (SUMO) Modification of Zinc Finger Protein 131 Potentiates Its Negative Effect on Estrogen Signaling |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2012-05 |
Neddylation positively regulates the ubiquitin E3 ligase activity of parkin |
JOURNAL OF NEUROSCIENCE RESEARCH
|
| 2012-04 |
The transcription factor STAT2 enhances proteasomal degradation of RCAN1 through the ubiquitin E3 ligase FBW7 |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2012-02 |
Protein kinase A phosphorylates Down syndrome critical region 1 (RCAN1) |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2012-01 |
Dyrk1A negatively regulates the actin cytoskeleton through threonine phosphorylation of N-WASP |
JOURNAL OF CELL SCIENCE
|
| 2012-01 |
Identification of RUNX3 as a component of the MST/Hpo signaling pathway |
Journal of Cellular Physiology
|
| 2011-08 |
Proteasome inhibition induces alpha-synuclein SUMOylation and aggregate formation |
JOURNAL OF THE NEUROLOGICAL SCIENCES
|
| 2011-03 |
Dyrk1A Positively Stimulates ASK1-JNK Signaling Pathway during Apoptotic Cell Death |
Experimental Neurobiology
|
| 2011-03 |
Human Polycomb protein 2 promotes α-synuclein aggregate formation through covalent SUMOylation |
BRAIN RESEARCH
|
| 2010-12 |
Stilbene Derivatives as Human 5-HT6 Receptor Antagonists from the Root of Caragana sinica |
Biological & Pharmaceutical Bulletin
|
| 2010-11 |
ASK1 negatively regulates the 26 S proteasome |
The Journal of biological chemistry
|
| 2010-10 |
Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells |
The Journal of biological chemistry
|
| 2010-09 |
Parkin Directly Modulates 26S Proteasome Activity |
JOURNAL OF NEUROSCIENCE
|
| 2010-03 |
Formation of parkin aggregates and enhanced PINK1 accumulation during the pathogenesis of Parkinson's disease |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
|
| 2009-12 |
Down syndrome candidate region-1 protein interacts with Tollip and positively modulates interleukin-1 receptor-mediated signaling |
Biochimica et Biophysica Acta - General Subjects
|
| 2009-10 |
Activation of adenylate cyclase by forskolin increases the protein stability of RCAN1 (DSCR1 or Adapt78) |
Febs Letters
|
| 2009-10 |
Function and regulation of Dyrk1A: towards understanding Down syndrome |
Cellular And Molecular Life Sciences
|
| 2009-09 |
The serine protease HtrA2/Omi cleaves Parkin and irreversibly inactivates its E3 ubiquitin ligase activity |
Biochemical And Biophysical Research Communications
|
| 2009-07 |
On the mechanism of internalization of alpha-synuclein into microglia: roles of ganglioside GM1 and lipid raft |
Journal Of Neurochemistry
|
| 2009-04 |
Molecular interaction between parkin and PINK1 in mammalian neuronal cells |
Molecular And Cellular Neuroscience
|
| 2009-03 |
Identification of the amino acid sequence motif of α-synuclein responsible for macrophage activation |
Biochemical And Biophysical Research Communications
|
| 2009-02 |
Two key genes closely implicated with the neuropathological characteristics in Down syndrome: DYRK1A and RCAN1 |
BMB REPORTS
|
| 2009-01 |
Modulation of Ca(v)3.1 T-type Ca2+ channels by the ran binding protein RanBPM |
Biochemical And Biophysical Research Communications
|
| 2008-12 |
Crystal structure of filamentous aggregates of human DJ-1 formed in an inorganic phosphate-dependent manner |
Journal of Biological Chemistry
|
| 2008-12 |
Disintegration of amyloid fibrils of alpha-synuclein by dequalinium |
Biochimica Et Biophysica Acta-General Subjects
|
| 2008-11 |
Down syndrome critical region 2 protein inhibits the transcriptional activity of peroxisome proliferator-activated receptor β in HEK293 cells |
Biochemical And Biophysical Research Communications
|
| 2008-10 |
cAMP-responding element-binding protein and c-Ets1 interact in the regulation of ATP-dependent MUC5AC gene expression |
Journal of Biological Chemistry
|
| 2008-06 |
CREB activates proteasomal degradation of DSCR1/RCAN1 |
Febs Letters
|
| 2008-05 |
A novel role of hippocalcin in bFGF-induced neurite outgrowth of H19-7 cells |
Journal Of Neuroscience Research
|
| 2008-05 |
Water-deprivation-induced expression of neuronal nitric oxide synthase in the hypothalamic paraventricular nucleus of rat |
Journal Of Neuroscience Research
|
| 2008-02 |
NF-kappa B-inducing kinase phosphorylates and blocks the degradation of down syndrome candidate region 1 |
Journal of Biological Chemistry
|
| 2008-01 |
Interaction of SOCS3 with NonO attenuates IL-1 beta-dependent MUC8 gene expression |
Biochemical And Biophysical Research Communications
|
| 2007-10 |
Dyrk1A overexpression in immortalized hippocampal cells produces the neuropathological features of Down syndrome |
MOLECULAR AND CELLULAR NEUROSCIENCE
|
| 2007-09 |
Functional interaction of neuronal ca(v)1.3 L-type calcium channel with ryanodine receptor type 2 in the rat hippocampus |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2007-08 |
Overexpression of DSCR1 blocks zinc-induced neuronal cell death through the formation of nuclear aggregates |
MOLECULAR AND CELLULAR NEUROSCIENCE
|
| 2007-07 |
Phospholipase D1 is associated with amyloid precursor protein in Alzheimer's disease |
NEUROBIOLOGY OF AGING
|
| 2007-04 |
alpha-synuclein overexpression reduces gap junctional intercellular communication in dopaminergic neuroblastoma cells |
NEUROSCIENCE LETTERS
|
| 2007-01 |
Zinc induces cell death in immortalized embryonic hippocampal cells via activation of Akt-GSK-3β signaling |
EXPERIMENTAL CELL RESEARCH
|
| 2007-01 |
JNK- and Rac1-dependent induction of immediate early gene pip92 suppresses neuronal differentiation |
JOURNAL OF NEUROCHEMISTRY
|
| 2006-12 |
alpha-Synuclein enhances dopamine D2 receptor signaling |
BRAIN RESEARCH
|
| 2006-11 |
Dyrk1A phosphorylates α-synuclein and enhances intracellular inclusion formation |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2006-11 |
Calpain-resistant fragment(s) of alpha-synuclein regulates the synuclein-cleaving activity of 20S proteasome |
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
|
| 2006-11 |
Functional modulation of parkin through physical interaction with SUMO-1 |
JOURNAL OF NEUROSCIENCE RESEARCH
|
| 2006-10 |
Huntingtin-interacting protein 1-mediated neuronal cell death occurs through intrinsic apoptotic pathways and mitochondrial alterations |
FEBS LETTERS
|
| 2006-05 |
APC inhibits ERK pathway activation and cellular proliferation induce by RAS |
JOURNAL OF CELL SCIENCE
|
| 2006-04 |
Amino acid sequence motifs and mechanistic features of the membrane translocation of alpha-synuclein |
JOURNAL OF NEUROCHEMISTRY
|
| 2006-04 |
20(S)-ginsenoside Rh-2, a newly identified active ingredient of ginseng, inhibits NMDA receptors in cultured rat hippocampal neurons |
EUROPEAN JOURNAL OF PHARMACOLOGY
|
| 2006-02 |
Dequalinium-induced protofibril formation of alpha-synuclein |
JOURNAL OF BIOLOGICAL CHEMISTRY
|
| 2006-01 |
Phospholipase D prevents etoposide-induced apoptosis by inhibiting the expression of early growth response-1 and phosphatase and tensin homologue deleted on chromosome 10 |
CANCER RESEARCH
|
| 2005-12 |
The expression patterns of human parkin in E. coli. and mammalian cells |
KOREAN JOURNAL OF LIFE SCIENCE
|
| 2005-10 |
Formation and regulation of Lewy body-like protein aggregates by the structural modification of α-synuclein |
Experimental Neurobiology
|
| 2005-07 |
Proteolytic cleavage of extracellular secreted alpha-synuclein via matrix metalloproteinases |
JOURNAL OF BIOLOGICAL CHEMISTRY
|